Residual antimicrobial activity after canal irrigation with chlorhexidine.
نویسندگان
چکیده
We previously reported that the in vitro antimicrobial activity of a 2.0% chlorhexidine endodontic irrigant was equivalent to that of 5.25% sodium hypochlorite. The purpose of this study was to determine if chlorhexidine irrigants could instill substantive antimicrobial activity in instrumented root canals in vitro. Human teeth were instrumented using 2.0% or 0.12% chlorhexidine as irrigants. After instrumentation, the root canals were filled with sterile water, and samples of the root canal fluid were absorbed with paper points at 6, 12, 24, 48, and 72 h after treatment. The paper points were assayed for antimicrobial activity by placing them on agar plate surfaces inoculated with Streptococcus mutans and measuring zones of inhibition. Antimicrobial activity was present in all 2.0% chlorhexidine-treated teeth throughout the 72-h testing period and in most teeth, in relatively lower concentrations, for 6 to 24 h after irrigation with 0.12% chlorhexidine. These results indicate that chlorhexidine instills substantive antimicrobial activity when used as an endodontic irrigant.
منابع مشابه
Effect of Different Obturation Materials on Residual Antimicrobial Activity of 2% Chlorhexidine in Dentin at Different Time Intervals: An Ex Vivo Study
OBJECTIVES The aim of this study was to evaluate the effect of gutta percha/AH26 and Resilon/RealSeal SE on residual antimicrobial activity of chlorhexidine (CHX) in human root dentin and suggest the best filling material when CHX is used as final irrigant. MATERIALS AND METHODS One-hundred and forty-four single-rooted human teeth were selected for this study. Canals were instrumented to the ...
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Microorganisms and their by-products are considered to be the major cause of pulp and periradicular pathosis. Hence, a major objective in root canal treatment is to disinfect the entire root canal system, which requires that all contents of the root canal system be eliminated as possible sources of infection. This goal may be accomplished using mechanical instrumentation and chemical irrigation...
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During the cleaning and shaping of the root canal, various irrigants have been used to reduce the residual debris, necrotic tissue, and bacteria, as well as to remove smear layer. Though sodium hypochlorite (NaOCl) is the most common irrigant used in root canal treatment, chlorhexidine (CHX) has been suggested as either an alternative or an adjunct root canal irrigant because of its antimicrobi...
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عنوان ژورنال:
- Journal of endodontics
دوره 23 4 شماره
صفحات -
تاریخ انتشار 1997